Data is a key driver of modern economy and AI/machine learning, however, a lot of this data is sensitive and handling the sensitive data has caused unprecedented challenges for both individuals and businesses, and these challenges will only get more severe as we move forward in the digital era. In this talk, I will talk about technologies needed for responsible data use including secure computing, differential privacy, federated learning, as well as blockchain technologies for data rights, and how to combine privacy computing technologies and blockchain to building a platform for a responsible data economy, to enable the creation of a new type of asset, i.e., data assets, more responsible use of data and fair distribution of value created from data.